Drinking Induced by Carbachol: Thirst Circuit or Ventricular Modification?
نویسندگان
چکیده
منابع مشابه
The Forebrain Thirst Circuit Drives Drinking through Negative Reinforcement.
The brain transforms the need for water into the desire to drink, but how this transformation is performed remains unknown. Here we describe the motivational mechanism by which the forebrain thirst circuit drives drinking. We show that thirst-promoting subfornical organ neurons are negatively reinforcing and that this negative-valence signal is transmitted along projections to the organum vascu...
متن کاملcarbachol-induced drinking in the rat
Carlo Polidori , Maurizio Massi I, Günter Lambrecht , Ernst Mutschier , Reinhold Tacke 3 and Carlo Melchiorre 4 1 Institute of Pharmacology, University of Camerino, 1-62032 Camerino ( MC). ltaly, 1 Institute of Pharmacology, University of Frankfurt, Theodor-Stern-Kai 7, D-6000 Frankfurt/ M. F.R.G., 3 Institute of lnorganic: Chemistry, University of Karlsruhe, Engesserstr., D-7500 Karlsruhe, F.R...
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Backgrounds/Aims: Prior to 1969, athletes were advised to avoid drinking during exercise. At least 4 subsequent events led to the adoption of a radically different approach. By 1996, all exercisers were advised to drink ‘as much as tolerable’ in order to insure that they did not lose any weight during exercise – the ‘zero percent dehydration’ doctrine. This advice requires that athletes drink e...
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In humans, thirst tends to be alleviated before complete rehydration is achieved. When sweating rates are high and ad libitum fluid consumption is not sufficient to replace sweat losses, a cumulative loss in body water results. Body mass losses of 2% or greater take time to accumulate. Dehydration of ≥ 2% body mass is associated with impaired thermoregulatory function, elevated cardiovascular ...
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The effects of intrahypothalamic carbachol microinjections were investigated in unprovoked cats. The carbachol evoked mydriasis, attention, vocalization, and piloerection, i.e. features of a typical defense were usually concomitant in evoked response, while the clear-cut aggressive or escape patterns appeared only once. No basic differences were observed in the set of manifestations induced by ...
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ژورنال
عنوان ژورنال: Science
سال: 1967
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.157.3790.838